Fully Funded PhD Position in Development and application of recombinant antibodies to map pathology-related changes in glycosaminoglycans on breast cancer cells Summary of PhD Program:
This studentship will aim to isolate a range of recombinant antibodies that bind to GAGs, producing highly specific probes. The post will use the very latest developments in antibody phage display technology, coupling the binding of vast antibody-phage libraries containing billions of potential binders with the screening power of next generation sequencing (a process termed next generation phage display, NGPD). The studentship will apply NGPD to target cell surface GAGs from breast cancer cell populations, identify specific binders, clone and express binders and finally, characterise binding against breast cancer cell populations and defined GAG structures.
Application Deadline: 14 August, 2024
